Skip to main content

Featured five-star hotel destinations

Destination inspiration for your trip – find a five-star hotel

The best five-star hotels in Panama

Check out our pick of great five-star hotels in Panama

Filter by:


Review score

Superb: 9+ Very good: 8+ Good: 7+ Pleasant: 6+
Our top picks Lowest price first Star rating and price Top reviewed

See the latest prices and deals by choosing your dates.

Amid the financial district of Panamá, Bristol Panama, a Registry Collection Hotel

has a spa centre and a sauna for guests to enjoy a massage, or they may use the fitness centre after a day’s work. Free WiFi is available. The breakfast was very good. The location was near everything and the rooms were very clean.

Show more Show less
9.2
Superb
1,069 reviews
Price from
US$211
per night

Situated in Panama City and with Ancon Hill reachable within 3.5 km, Hotel San Felipe features concierge services, non-smoking rooms, a terrace, free WiFi throughout the property and a restaurant. This 5-star hotel offers room service and a 24-hour front desk. Guests can have a drink at the bar. The Hotel San Felipe is beautiful, comfortable, and perfectly located right in the heart of Casco Viejo. The room we had was extremely quiet at night. The bed was very comfortable. The staff were lovely, welcoming, friendly, and attentive. We really felt very at home. I'd happily stay here again.

Show more Show less
9
Superb
580 reviews
Price from
US$150
per night

Set in Panama City and with Ancon Hill reachable within 4 km, Hotel La Compañía Casco Antiguo features concierge services, allergy-free rooms, a terrace, free WiFi throughout the property and a restaurant. This 5-star hotel offers a 24-hour front desk and a business centre. The hotel offers an outdoor swimming pool, fitness centre, nightclub and room service. Location. Restaurants and bars. Room. Breakfast. Friendly staff.

Show more Show less
9.4
Superb
504 reviews
Price from
US$365
per night

Situated in Panama City, 4 km from Ancon Hill, Sofitel Legend Casco Viejo, Panama City features accommodation with an outdoor swimming pool, private parking, a fitness centre and a garden. Featuring a restaurant, the property also has a terrace and a bar. The accommodation offers a 24-hour front desk, airport transfers, room service and free WiFi. Beautiful, clean and extremely elegant.

Show more Show less
9.5
Exceptional
847 reviews
Price from
US$425
per night

Located in Panama City, 3.5 km from Estadio Rommel Fernandez, The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City provides accommodation with free bikes, free private parking, an outdoor swimming pool and a fitness centre. With a garden, the property also features a terrace, as well as a bar. The accommodation offers a 24-hour front desk, a shuttle service, room service and free WiFi throughout the property. This is how you run a hotel. From the very first moment you feel welcome, appreciated and at home. The staff was great. You feel they are happy to work there and happy to have you as a guest. Little shout out to wonderful Nayeli at the reception desk, she is a gem. Everything in the hotel, the area, the pool, the restaurants, is neat and organized and the rooms are clean. The breakfast is amazing, a big variety, including nice Panamanian food! After a few other Marriott hotels in Panama, this felt like a different league. We had an amazing time here. This will be our #1 choice hotel when we ever return to Panama .

Show more Show less
9.4
Superb
443 reviews
Price from
US$224.25
per night

The luxury 20-storey Hyatt Regency Panama City is set in central Panama City, 1 km from Bahía de Panamá Bay and its port. It features an outdoor pool, spa, and rooms with seating areas.

Hyatt Regency Panama City has attractive, traditional décor with wooden furnishings. Each air-conditioned room has a flat-screen TV, a desk and a marble bathroom. Beautiful, clean, modern and very attentive staff! Breakfast was also exceptional! I would definitely stay again!

Show more Show less
9.1
Superb
122 reviews
Price from
US$180
per night

Situated in Panama City, 6.4 km from Ancon Hill, La Residence Panamá features accommodation with a fitness centre, free private parking, a shared lounge and a restaurant. This 5-star hotel offers room service, a 24-hour front desk and free WiFi. Guests can have a drink at the bar. Great location! Super clean and comfortable property. Very kind and attentive staff! Special thank you to Alexander, George and Eddie for their warm welcome! Would definitely stay here again.

Show more Show less
9.8
Exceptional
12 reviews
Price from
US$148
per night

Set 3.7 km from Ancon Hill, Hotel Plaza Herrera offers 5-star accommodation in Panama City and features a bar. Among the facilities of this property are a restaurant, room service and a 24-hour front desk, along with free WiFi throughout the property. Private parking can be arranged at an extra charge. This hotel is brand new, renovated on a restored building in the Casco area of Panama city. The location is amazing, on a quite square, but a minute walk from all the restaurants and attractions of the area. Stayed as a family in a big room, two floors, two bathrooms, huge balcony with a view. Facilities are elegant and beautiful. Breakfast is delicious, with free choice from an a-la-carte menu. Would definitely return here.

Show more Show less
9.3
Superb
24 reviews
Price from
US$330
per night

Located in Panama City, 8 km from Bridge of the Americas, Waymore Hotel Spa & Casino provides accommodation with an outdoor swimming pool, free private parking, a fitness centre and a restaurant. Each accommodation at the 5-star hotel has city views, and guests can enjoy access to a bar and to a casino. The accommodation offers a 24-hour front desk, airport transfers, room service and free WiFi throughout the property. We loved everything about Waymore Hotel Spa and Casino. The place was beautiful and the breakfast was great. Staff were very helpful. Even though we couldn't speak Spanish, the staff tried their very best to facilitate us. There was a shuttle to go to Albrook mall every day for 11am that you had to book the day before and we took a taxi to go back to the hotel after shopping. We literally shopped till we dropped. There was also a free shuttle from the airport to the hotel that we also arranged with the hotel in advance and we took an Uber ($20us) back to the airport. Everything was exactly as in their pictures and description

Show more Show less
8.7
Fabulous
2,298 reviews
Price from
US$97
per night

Located in Panama City, 6.5 km from Ancon Hill, Gran Evenia Panamá Hotel provides accommodation with an outdoor swimming pool, free private parking, a fitness centre and a garden. Featuring a shared lounge, the 5-star hotel has air-conditioned rooms with free WiFi, each with a private bathroom. The hotel features city views, a terrace and a 24-hour front desk. Breakfast was amazing. so much variety and great tasting! the amenities are new. staff were really friendly.The pool and gym were great and hardly ever occupied. only ever saw someone there twice over my 5 day stay.

Show more Show less
8.6
Fabulous
1,262 reviews
Price from
US$87
per night

Most booked five-star hotels in Panama this month

FAQs about five-star hotels in Panama

Five-Star Hotels that guests love in Panama