Skip to main content

Featured boutique hotel destinations

Destination inspiration for your trip – find a boutique hotel

The best boutique hotels in Florida Keys

Check out our pick of great boutique hotels in Florida Keys

Filter by:


Review score

Superb: 9+ Very good: 8+ Good: 7+ Pleasant: 6+
Our top picks Lowest price first Star rating and price Top reviewed

See the latest prices and deals by choosing your dates.

This adult-only, pet friendly, smoke-free property is located in the heart of Key West less than 1.6 km from the Southernmost Point. Guests will enjoy a daily breakfast including pastries, organic fruit, and dessert cakes during their stay. The building and location. What a relaxing environment, lace to be.

Show more Show less
9.1
Superb
1,040 reviews
Price from
US$349
per night

Located just 2 minutes’ walk from the Ernest Hemingway Home and Museum, this adult-only inn features free parking and a shared outdoor swimming pool. Free Wi-Fi is also available.

A microwave, refrigerator and coffee-making facilities come standard in each room at Douglas House. Guests rooms also include a cable TV. Great location, only few minutes to Southernmost Point of the Continental U.S.A. Mallory Square is about 20 min walk along Duval St, where most of restaurant are. Staff at the Douglas House were exceptional, Jose is very friendly and helpful.

Show more Show less
9.1
Superb
2,566 reviews
Price from
US$259
per night

Located in Key West, this Florida adult-only inn offers complimentary, light continental breakfast and free Wi-Fi access. Duval Street is 2 minutes’ drive from the property and The Ernest Hemingway Home and Museum is 3 minutes’ drive away. Pool is fantastic. Hotel got perfect atmosphere and is setup in beautiful garden.

Show more Show less
9.2
Superb
1,058 reviews
Price from
US$249
per night

Located in the heart of historic Key West, guests will be 1 minutes’ walk from Duval Street. A heated pool, daily continental breakfast, and free WiFi are provided.

All rooms feature a private bath, small refrigerator, and microwave. Apartments at Key West Villas include a fully-equipped kitchen and seating area. If I could give more than 10 I would! Everything was perfect: the location (in the heart of Key West, parking space available), the rooms (they’re even nicer as on the homepage), the poolside.. everything was so tasteful and clean. And of course the hosts ! They make everything to make you feel home. Snacks and drinks available all day long, happy hour every day and the bottle of wine offered upon arrival!! We just can strongly recommend this lovely place.

Show more Show less
9.7
Exceptional
322 reviews
Price from
US$379
per night

This historical Key West bed and breakfast is 1 mile from the Southernmost Point and 3 minute’s walk from iconic Duval Street. The Artist House guests will enjoy a daily continental breakfast and spa hot tub. The place is INCREDIBLE! Charming, beautiful, interesting, fun and so much more. I have been to Key West dozens of times and this is the best place I stayed by far, I would take it over any fancy hotel I have stayed in the area. Sophia and Shawn (or Sean?) are perfect hosts. The breakfast is great, with fruit, mimosas, great coffee and much more. They also hace a charming Happy Hour that they serve cheese and crackers and good wine.

Show more Show less
9.4
Superb
206 reviews
Price from
US$292.95
per night

Ambrosia Key West only allows pets in designated rooms. If you plan on bringing a pet please read the room descriptions carefully to ensure that you will be allowed to have a pet in the room you reserve,and offers guests free WiFi. Guests can stroll through picturesque tropical courtyards and lounge in the hot tub or poolside, where snacks and refreshments are offered daily in the early afternoon. Location was great. The room fabulous. It would be nice if a mirror could be added. Beautiful garden terrace. Nice spa in the garden. Very friendly and helpful staff.

Show more Show less
9
Superb
747 reviews
Price from
US$339
per night

Located right off Duval Street, the Andrews Inn and Garden Cottages are less than 5 minutes’ walk from various dining and entertainment options. Guests can enjoy free WiFi and an outdoor pool.

A flat-screen TV and an iPod docking station are featured in each classic room at this Key West bed and breakfast. Guests will also enjoy the convenience of a refrigerator in their room. Rooms also have a clock radio with auxiliary cables. Great location, amazing Staff, very well decorated place and good breakfast!

Show more Show less
9.5
Exceptional
153 reviews
Price from
US$398.09
per night

Located in Key West, Florida, this adult-only hotel offers two outdoor pools. Duval Street is a 1-minute walk away, and Key West Butterfly and Nature Conservatory is 3 minutes’ drive from the hotel.

A private balcony or patio with property views is provided in all rooms at The Gardens Hotel Key West. A flat-screen cable TV, ironing facilities, and a refrigerator are also featured in each room. The hotel is just amazing. stunning accommodation, spacious, exceptionally clean. positively one of the best hotels I have ever stayed in. There was entertainment both nights we stayed. The gardens are truly wonderful

Show more Show less
9.3
Superb
116 reviews
Price from
US$486.25
per night

This all-suite hotel in Key West is only 1 block from the Atlantic Ocean and Duval Street. Each suite is equipped with a full kitchen and 48-inch flat-screen cable TVs.

Two outdoor heated pools are surrounded by gardens at Santa Maria Suites Resort. A full-service concierge. Everythink was absolutely perfect 10/10. the hotel itself , rooms, equipment pool, soft dronks, location - PERFECT

Show more Show less
9.3
Superb
676 reviews
Price from
US$529
per night

This Marathon, Florida waterfront resort offers boat rentals, an outdoor swimming pool, and free WiFi access. Sombrero Beach is 6.9 km from the property.

A flat-screen TV, microwave, and small refrigerator are provided in every room at this Marathon Captain Pip's Marina and Hideaway. Extras include a toaster and coffee machine. Loved the aqua lodge for my family of 5.

Show more Show less
8.3
Very good
1,280 reviews
Price from
US$149
per night

Most booked boutique hotels in Florida Keys this month

Boutique Hotels that guests love in Florida Keys